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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0776
All Species:
31.21
Human Site:
Y249
Identified Species:
57.22
UniProt:
O94874
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94874
NP_056138.1
794
89595
Y249
A
V
F
V
P
D
I
Y
S
R
T
Q
S
T
W
Chimpanzee
Pan troglodytes
XP_518643
794
89625
Y249
A
V
F
V
P
D
I
Y
S
R
T
Q
S
T
W
Rhesus Macaque
Macaca mulatta
XP_001100312
793
89480
Y249
A
V
F
V
P
D
I
Y
S
R
T
Q
S
T
W
Dog
Lupus familis
XP_532236
830
93092
D293
T
V
V
G
G
R
Q
D
K
A
V
F
V
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CCJ3
793
89502
Y249
A
V
F
V
P
D
I
Y
S
R
T
Q
S
T
W
Rat
Rattus norvegicus
B2GV24
793
89567
Y249
A
V
F
V
P
D
I
Y
S
R
T
Q
S
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510895
871
97174
Y325
A
V
F
V
P
D
I
Y
S
K
T
Q
S
N
W
Chicken
Gallus gallus
Q5ZMG1
789
89086
Y249
A
V
F
V
P
D
I
Y
A
R
T
Q
S
N
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6PGY6
793
88661
Y249
A
I
Y
I
P
D
I
Y
S
K
A
Q
S
T
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VI55
782
87464
A250
H
I
Y
A
K
T
Q
A
D
W
V
N
S
F
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17750
735
80983
S223
I
A
F
E
N
L
Q
S
L
G
E
I
P
G
T
Sea Urchin
Strong. purpuratus
XP_780358
558
62888
E64
T
P
S
Q
V
V
K
E
I
R
D
E
L
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX73
804
89055
F253
T
H
W
T
P
S
A
F
A
T
A
Q
K
E
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
86
N.A.
90.5
90.6
N.A.
69.6
74.6
N.A.
62.9
N.A.
35.2
N.A.
23.6
35.8
Protein Similarity:
100
99.7
99.6
90.5
N.A.
95.9
96.4
N.A.
81.2
87.7
N.A.
80.2
N.A.
58.3
N.A.
43.9
52.7
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
86.6
86.6
N.A.
66.6
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
26.6
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
8
0
8
0
0
8
8
16
8
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
62
0
8
8
0
8
0
0
0
8
% D
% Glu:
0
0
0
8
0
0
0
8
0
0
8
8
0
8
0
% E
% Phe:
0
0
62
0
0
0
0
8
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
8
8
0
0
0
0
8
0
0
0
8
0
% G
% His:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
8
0
0
62
0
8
0
0
8
0
8
8
% I
% Lys:
0
0
0
0
8
0
8
0
8
16
0
0
8
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
8
0
16
0
% N
% Pro:
0
8
0
0
70
0
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
8
0
0
24
0
0
0
0
70
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
54
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
8
54
0
0
0
70
0
0
% S
% Thr:
24
0
0
8
0
8
0
0
0
8
54
0
0
47
8
% T
% Val:
0
62
8
54
8
8
0
0
0
0
16
0
8
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
62
% W
% Tyr:
0
0
16
0
0
0
0
62
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _